Primary Identifier | MGI:3837395 | Allele Type | Targeted |
Attribute String | Conditional ready, No functional change | Gene | Lrp5 |
Transmission | Germline | Strain of Origin | Not Specified |
Is Recombinase | false | Is Wild Type | false |
molecularNote | A loxP site was inserted in exon 1 just in front of the ATG start site and a floxed neo cassette and cDNA containing a mutant form of Lrp5 with a flag tag were inserted in intron 1. The cDNA included 2 mutations 5 glycine and 171 valine. The neo cassette was later removed by Cre mediated recombination. |