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Allele : Shc2<em1Adiuj> SHC (Src homology 2 domain containing) transforming protein 2; endonuclease-mediated mutation 1, MODEL-AD Center
Primary Identifier  MGI:6315852 Allele Type  Endonuclease-mediated
Gene  Shc2 Strain of Origin  B6(SJL)-Apoe<tm1.1(APOE*4)Adiuj> Trem2<em1Adiuj>/J
Is Recombinase  false Is Wild Type  false
molecularNote  CRISPR/Cas9 genome editing is used to introduce a V433M point mutation in to the gene.
  • mutations:
  • Insertion,
  • Nucleotide substitutions
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

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Trail: Allele

0 Driven By

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Trail: Allele




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