First Author | Kay PH | Year | 1991 |
Journal | Gene | Volume | 99 |
Issue | 2 | Pages | 273-7 |
PubMed ID | 1673668 | Mgi Jnum | J:11143 |
Mgi Id | MGI:59585 | Doi | 10.1016/0378-1119(91)90138-2 |
Citation | Kay PH, et al. (1991) Genetic polymorphism of the murine myogenic gene Myo-D1. Gene 99(2):273-7 |
abstractText | Polymorphism of the myogenic gene, Myo-D1, has been sought to examine genetic mechanisms which control skeletal muscle development. By Southern analysis, three restriction-fragment length polymorphisms (RFLPs) have been found in various mouse strains using the TaqI, SacI and BglII restriction endonucleases and a full-length cDNA Myo-D1 probe. Reference to the distribution of RFLPs in different mouse strains derived from Mus mus (M.m.) domesticus and M.m. musculus subspecies suggests that Myo-D1 rearrangements are subject to nonrandom association. The biological significance of RFLP of the Myo-D1 gene is yet to be determined. |