| Primary Identifier | IPR025160 | Type | Domain |
| Short Name | AATF |
| description | This leucine zipper-containing domain is found in apoptosis antagonizing transcription factor (AATF, also known as Che-1) and related proteins. AATF may function as a general inhibitor of the histone deacetylase HDAC1 []. AATF has been shown to inhibit the abberant production of the amyloid beta peptide 1-42 by direct interaction with Par4 []. This interaction occurs via the leucine zipper. |
