| Primary Identifier | IPR028788 | Type | Family |
| Short Name | CDK6 |
| description | Cyclin-dependent kinase 6 (CDK6) is a D-Cyclin-activated kinase that is involved in driving the cell cycle through inactivation of pRB in G1 phase [, ]. It has been implicated in cell proliferation []and tumor angiogenesis []. It is also involved in cell differentiation through regulation of gene expression []. CDK6 interacts with the p65 subunit of NFkB in the nucleus, and is found at promoters of many transcriptionally active NFkB target genes []. |
