| Type | MGI:General | Description | in the peripheral nerves, mutant mice exhibit a variable and complex degree of myelin infoldings and outfoldings, mainly in the paranodal regions defects usually are associated with large caliber axons; small caliber and non-myelinated axons appear unaffected defects are progressive with age; rare defects are noted at 3 weeks of age and older mice at 6 months of age tend to have more affected nerve fibers |
