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Protein Coding Gene : Msra methionine sulfoxide reductase A
Primary Identifier  MGI:106916 Organism  mouse, laboratory
Chromosome  14 NCBI Gene Number  110265
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0)

Enables peptide-methionine (S)-S-oxide reductase activity. Predicted to be involved in cellular response to oxidative stress. Located in mitochondrion. Is expressed in several structures, including musculoskeletal system; nervous system; respiratory system; sensory organ; and testis. Orthologous to human MSRA (methionine sulfoxide reductase A).
PHENOTYPE: Mice homozygous for disruptions in this allele display an increased sensitivity to oxidative stress, reductions in related enzyme levels, and reduced life spans. [provided by MGI curators]
  • synonyms:
  • MGI:1914949,
  • MGD-MRK-35377,
  • RIKEN cDNA 2310045J23 gene,
  • RIKEN cDNA 6530413P12 gene,
  • 2310045J23Rik,
  • 6530413P12Rik,
  • MGI:1923458,
  • Msra,
  • methionine sulfoxide reductase A,
  • MSR-A
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Features --> Cross References

Genome

Sequence Feature Displayer

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1 Involved In Mutations

Trail: ProteinCodingGene

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1 Transgenic Expressors

Trail: ProteinCodingGene

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

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Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

2 Pathways

Trail: ProteinCodingGene

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Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

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