First Author | Branda CS | Year | 2004 |
Journal | Dev Cell | Volume | 6 |
Issue | 1 | Pages | 7-28 |
PubMed ID | 14723844 | Mgi Jnum | J:87967 |
Mgi Id | MGI:3028752 | Doi | 10.1016/s1534-5807(03)00399-x |
Citation | Branda CS, et al. (2004) Talking about a revolution: The impact of site-specific recombinases on genetic analyses in mice. Dev Cell 6(1):7-28 |
abstractText | Site-specific recombinase systems (Cre-loxP, Flp-FRT, and phi C31-att) are transforming both forward and reverse genetics in mice. By enabling high-fidelity DNA modifications to be induced in vitro or in vivo, these systems have incited a wave of new biology, advancing our understanding of gene function, genetic relationships, development, and disease. |