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Allele : Igk<tm2.1Cog> immunoglobulin kappa chain complex; targeted mutation 2.1, Michel Cogne
Primary Identifier  MGI:5788337 Allele Type  Targeted
Attribute String  Humanized sequence, Inserted expressed sequence Gene  Igk
Transmission  Germline Strain of Origin  129P2/OlaHsd
Is Recombinase  false Is Wild Type  false
molecularNote  The following sequences were inserted between Igkj segments and the Igk-Eik super-enhancer: murine Igh core switch region mu, human IGK-EIK super-enhancer, human IGK constant region, Igkv 4-63 promoter sequence and 1st exon with a STOP sequence, murine Igh core switch region gamma3, and a loxP site flanked neomycin resistance gene cassette. Subsequent cre-mediated recombination removed the neo cassette.
  • mutations:
  • Intragenic deletion,
  • Insertion
  • synonyms:
  • Igkj5<tm2.1Cog>,
  • Neo<R>-deleted KIKS,
  • Neo<R>-deleted KIKS,
  • Igkj5<tm2.1Cog>
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1 Feature

Trail: Allele

Genome

2 Expresses

Trail: Allele

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

4 Publication categories

Trail: Allele




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