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Protein Coding Gene : Piwil1 piwi-like RNA-mediated gene silencing 1

Primary Identifier  MGI:1928897 Organism  mouse, laboratory
Chromosome  5 NCBI Gene Number  57749
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0)

Enables several functions, including RNA binding activity; mRNA cap binding complex binding activity; and protein kinase binding activity. Involved in piRNA-mediated retrotransposon silencing by heterochromatin formation; primary piRNA processing; and sperm DNA condensation. Located in chromatoid body; dense body; and nucleus. Is expressed in several structures, including central nervous system; genitourinary system; hemolymphoid system gland; and lung. Orthologous to human PIWIL1 (piwi like RNA-mediated gene silencing 1).
PHENOTYPE: Homozygotes for a targeted null mutation exhibit male sterility due to a block in spermatogenesis beginning at the round spermatid stage. [provided by MGI curators]
  • synonyms:
  • Piwil1,
  • piwi-like RNA-mediated gene silencing 1,
  • MIWI

Features --> Cross References

Genome

Sequence Feature Displayer

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0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

2 Involved In Mutations

0 Strain

0 Transcripts

2 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

0 Pathways

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

Other

0 Driver For