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Protein Coding Gene : Ankrd17 ankyrin repeat domain 17

Primary Identifier  MGI:1932101 Organism  mouse, laboratory
Chromosome  5 NCBI Gene Number  81702
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.0.0)

Predicted to enable chromatin binding activity. Acts upstream of or within blood vessel maturation and negative regulation of smooth muscle cell differentiation. Located in male germ cell nucleus. Is expressed in several structures, including alimentary system; gonad; liver; nervous system; and septum transversum. Orthologous to human ANKRD17 (ankyrin repeat domain 17).
PHENOTYPE: Mice homozygous for a null mutation display embryonic lethality during organogenesis with hemorrhages, impaired vascular smooth muscle cell development, impaired vascular integrity, and growth retardation. [provided by MGI curators]
  • synonyms:
  • MGI:2444962,
  • A130069E23Rik,
  • MGI:2141077,
  • MGI:2140756,
  • RIKEN cDNA 4933425K22 gene,
  • 4933425K22Rik,
  • ankyrin repeat domain 17,
  • RIKEN cDNA A130069E23 gene,
  • AA407558,
  • expressed sequence AA407558,
  • MGI:1918421,
  • expressed sequence AA516750,
  • expressed sequence AU040470,
  • MGI:2140727,
  • Ankrd17,
  • AA516750,
  • mKIAA0697,
  • Gtar,
  • AU040470

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Genome

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4 Involved In Mutations

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Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

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Canonical gene --> Transcripts in specific strains.

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