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Protein Coding Gene : Pnp2 purine-nucleoside phosphorylase 2
Primary Identifier  MGI:3712328 Organism  mouse, laboratory
Chromosome  14 NCBI Gene Number  667034
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0)

Predicted to enable several functions, including heterocyclic compound binding activity; phosphate ion binding activity; and purine-nucleoside phosphorylase activity. Predicted to be involved in several processes, including nicotinamide riboside catabolic process; nucleobase-containing compound biosynthetic process; and positive regulation of interleukin-2 production. Predicted to be located in cytosol and extracellular region. Predicted to be active in cytoplasm. Is expressed in alimentary system and intestine. Human ortholog(s) of this gene implicated in purine nucleoside phosphorylase deficiency and purine-pyrimidine metabolic disorder. Orthologous to human PNP (purine nucleoside phosphorylase).
  • synonyms:
  • Pnp2,
  • purine-nucleoside phosphorylase 2
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Genome

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0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

1 Involved In Mutations

Trail: ProteinCodingGene

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0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

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Function

Mouse features --> Functions (GO terms)

Homology

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Interactions

11 Pathways

Trail: ProteinCodingGene

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Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

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