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Protein Coding Gene : Prdx2 peroxiredoxin 2
Primary Identifier  MGI:109486 Organism  mouse, laboratory
Chromosome  8 NCBI Gene Number  21672
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0)

Predicted to enable thioredoxin peroxidase activity. Involved in positive regulation of blood coagulation and removal of superoxide radicals. Acts upstream of or within several processes, including hydrogen peroxide catabolic process; regulation of signal transduction; and respiratory burst involved in inflammatory response. Located in mitochondrion and myelin sheath. Is expressed in several structures, including alimentary system; central nervous system; limb; reproductive system; and sensory organ. Orthologous to human PRDX2 (peroxiredoxin 2).
PHENOTYPE: Homozygous null mice have hemolytic anemia and exhibit enlarged spleens due to congestion of the red pulp. [provided by MGI curators]
  • synonyms:
  • Prdx2,
  • PRP,
  • PrxII,
  • Trx dependent peroxide reductase 1,
  • TR,
  • thioredoxin reductase,
  • thioredoxin peroxidase 1,
  • protector protein,
  • thioredoxin dependent peroxide reductase 1,
  • MGD-MRK-39485,
  • thiol specific antioxidant protein,
  • TDX1,
  • TPx,
  • peroxiredoxin 2,
  • TSA,
  • Prx II-1,
  • thioredoxin peroxidase,
  • MGI:2138384,
  • Tdpx1,
  • AL022839,
  • expressed sequence AL022839
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