Primary Identifier | IPR022175 | Type | Domain |
Short Name | BCAS3 |
description | This domain is found towards the C-terminal of BCAS3 and ATG18-like proteins from plants. In BCAS3, this domain seems to be important for PHAF1 interactions [].This entry includes BCAS3 from animals and AT18F/G/H from Arabidopsis. BCAS3 is a microtubule associated cell migration factor that has been linked to the development of breast cancer and angiogenesis []. It forms a complex with PHAF1 and associates with the preautophagosomal structure during both non-selective and selective autophagy [].AT18F/G/H are linked to autophagy []. |