Primary Identifier | IPR026781 | Type | Family |
Short Name | PNRC2 |
description | Proline-rich nuclear receptor coactivator 2 (PNRC2) may serve as a bridge between the mRNA decapping complex and the NMD (nonsense-mediated mRNA decay) machinery. It interacts with and triggers movement of hyperphosphorylated Upf1, an important player in NMD, into P bodies. It also interacts with Dcp1a, which is part of the decapping complex []. Moreover, PNRC2 may play a role in controlling the energy balance between energy storage and energy expenditure []. |