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Protein Domain : Proline-rich nuclear receptor coactivator 2

Primary Identifier  IPR026781 Type  Family
Short Name  PNRC2
description  Proline-rich nuclear receptor coactivator 2 (PNRC2) may serve as a bridge between the mRNA decapping complex and the NMD (nonsense-mediated mRNA decay) machinery. It interacts with and triggers movement of hyperphosphorylated Upf1, an important player in NMD, into P bodies. It also interacts with Dcp1a, which is part of the decapping complex []. Moreover, PNRC2 may play a role in controlling the energy balance between energy storage and energy expenditure [].

0 Child Features

1 Parent Features

1 Protein Domain Regions