| First Author | Kozak CA | Year | 1985 |
| Journal | Mol Cell Biol | Volume | 5 |
| Issue | 4 | Pages | 894-7 |
| PubMed ID | 2985974 | Mgi Jnum | J:7831 |
| Mgi Id | MGI:56300 | Doi | 10.1128/mcb.5.4.894 |
| Citation | Kozak CA, et al. (1985) Genetic mapping of a cellular DNA region involved in induction of thymic lymphomas (Mlvi-1) to mouse chromosome 15. Mol Cell Biol 5(4):894-7 |
| abstractText | Mlvi-1 defines a genetic locus representing a common domain for proviral DNA integration in Moloney murine leukemia virus-induced rat thymic lymphomas. Cellular sequences homologous to Mlvi-1 are present in mouse DNA, and we have used hamster-mouse somatic cell hybrids to chromosomally map Mlvi-1 in the mouse genome. Results demonstrated that Mlvi-1 maps to mouse chromosome 15 and that it is distinct from the Mlvi-2 integration region and from the cellular oncogenes c-myc and c-sis, which also map to this chromosome. Therefore, Mlvi-1 may contain novel sequences involved in the establishment and maintenance of virus-induced murine tumors, many of which contain abnormalities of chromosome 15. |
