Primary Identifier | IPR030334 | Type | Family |
Short Name | ATP2C2 |
description | Secretory pathway Ca-ATPase 2 (SPCA2), also known as ATP2C2, belongs to the IIA subfamily of P-type ATPases, whose members are Ca2+ ATPases that catalyse the hydrolysis of ATP coupled with the transport of calcium across the membrane [].In mammals, SPCA2 plays a role in lactation []. Its expression is linked to tumorigenesis in mammary tumours []. Mutations in the SPCA2 gene are linked to speech and language disorders []. |