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Allele : Prm1<em3Ssha> protamine 1; endonuclease-mediated mutation 3, Saher Sue Hammoud

Primary Identifier  MGI:7520863 Allele Type  Endonuclease-mediated
Attribute String  Dominant negative Gene  Prm1
Strain of Origin  C57BL/6N Is Recombinase  false
Is Wild Type  false
molecularNote  CRISPR/Cas9 technology a truncated protein in which residues 46-51 in the C-terminus are deleted. Truncated protein expression is stable but RNA levels are reduced. Incorporation into chromatin occurs but at lower efficiency.
  • mutations:
  • Intragenic deletion
  • synonyms:
  • P1<delta46-51>,
  • P1<delta46-51>
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

2 Publication categories

Trail: Allele