Primary Identifier | MGI:7520863 | Allele Type | Endonuclease-mediated |
Attribute String | Dominant negative | Gene | Prm1 |
Strain of Origin | C57BL/6N | Is Recombinase | false |
Is Wild Type | false |
molecularNote | CRISPR/Cas9 technology a truncated protein in which residues 46-51 in the C-terminus are deleted. Truncated protein expression is stable but RNA levels are reduced. Incorporation into chromatin occurs but at lower efficiency. |