Primary Identifier | MGI:4835278 | Allele Type | Targeted |
Attribute String | Null/knockout | Gene | Prox2 |
Transmission | Germline | Strain of Origin | 129S4/SvJae-Tg(Prm-cre)70Og |
Is Recombinase | false | Is Wild Type | false |
molecularNote | A 4.7 kb BamHI-HindIII genomic segment containing the first coding exon was replaced by a floxed neomycin selection cassette. The translation start site and part of a homeodomain were removed. The Prm1-cre transgene present in PC3 ES cells excised the selection cassette when it was expressed in spermatids of male chimeras. |