Primary Identifier | MGI:5792884 | Allele Type | Targeted |
Attribute String | Null/knockout | Gene | Rfx2 |
Transmission | Germline | Strain of Origin | (129X1/SvJ x 129S1/Sv)F1-Kitl<+> |
Is Recombinase | false | Is Wild Type | false |
molecularNote | An FRT-flanked neomycin resistance cassette was inserted downstream of a floxed exon 7. Flp-mediated recombination removed the selection cassette. Cre-mediated recombination removed exon 7. Western blot analysis of testis protein extracts confirmed the absence of full-length protein in homozygous mutant mice. |