| First Author | Jang W | Year | 1996 |
| Journal | Genomics | Volume | 36 |
| Issue | 2 | Pages | 366-8 |
| PubMed ID | 8812468 | Mgi Jnum | J:35452 |
| Mgi Id | MGI:82901 | Doi | 10.1006/geno.1996.0477 |
| Citation | Jang W, et al. (1996) Aup1, a novel gene on mouse chromosome 6 and human chromosome 2p13. Genomics 36(2):366-8 |
| abstractText | We have cloned a novel mouse cDNA, Aup1, encoding a predicted protein of 410 amino acid residues. The 1.5-kb Aup1 transcript is ubiquitously expressed in mouse tissues, An evolutionary relationship to the Caenorhabditis elegans predicted protein F44b9.5 is indicated by the 35% identity and 53% conservation of the amino acid sequences. Nineteen related human ESTs spanning 80% of the protein have also been identified, with a predicted amino acid sequence identity of 86% between the human and the mouse proteins. The gene has been mapped to a conserved linkage group on human chromosome 2p13 and mouse Chromosome 6. Aup1 was eliminated as a candidate gene for two closely linked disorders, human LGMD2B and mouse mnd2. (C) 1996 Academic Press, Inc. |
