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Protein Coding Gene : Prg2 proteoglycan 2, bone marrow

Primary Identifier  MGI:103294 Organism  mouse, laboratory
Chromosome  2 NCBI Gene Number  19074
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0)

Predicted to enable carbohydrate binding activity. Predicted to be an extracellular matrix structural constituent conferring compression resistance. Acts upstream of or within defense response to nematode and regulation of cytokine production. Located in collagen-containing extracellular matrix. Is expressed in several structures, including immune system; liver; lung; and male reproductive gland or organ. Orthologous to human PRG2 (proteoglycan 2, pro eosinophil major basic protein).
PHENOTYPE: Mice homozygous for disruptions in this gene display an essentially normal phenotype although fine structure changes occur in eosinophils. [provided by MGI curators]
  • synonyms:
  • Prg2,
  • mMBP,
  • mMBP-1,
  • proteoglycan 2, bone marrow,
  • MGD-MRK-24176,
  • EMBP

Features --> Cross References

Genome

Sequence Feature Displayer

JG Browse Displayer

0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

4 Involved In Mutations

0 Strain

0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

3 Pathways

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

Other

0 Driver For