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Publication : The effects of aspirin on the development of the mouse third molar. A potential screening system for weak teratogens.

First Author  Berry CL Year  1979
Journal  Arch Toxicol Volume  42
Issue  3 Pages  185-90
PubMed ID  475592 Mgi Jnum  J:24832
Mgi Id  MGI:72572 Doi  10.1007/bf00353710
Citation  Berry CL, et al. (1979) The effects of aspirin on the development of the mouse third molar. A potential screening system for weak teratogens. Arch Toxicol 42(3):185-90
abstractText  Aspirin is teratogenic at high doses in rodents. A dose related effect is shown at much lower levels in an animal testing system which permits subthreshold effects on development to be measured. This system, which depends on changes in tooth size in the mouse, has advantages in assessing weak or cumulative teratogens.
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