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Protein Domain : WAS/WASL-interacting protein family member 2

Primary Identifier  IPR028294 Type  Family
Short Name  WIPF2
description  WAS/WASL-interacting protein family member 2 (WIPF2, also known as WICH or WIRE) contains a verprolin-homology (V) region. It plays an important role in actin-microspike formation through cooperation with WASL (neural Wiskott-Aldrich syndrome protein, also known as N-WASP) []. It plays an active role in the formation of cell surface protrusions downstream of activated PDGFB (platelet-derived growth factor B) receptors [].
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0 Child Features

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2 Protein Domain Regions

Trail: ProteinDomain




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