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Publication : Talking about a revolution: The impact of site-specific recombinases on genetic analyses in mice.

First Author  Branda CS Year  2004
Journal  Dev Cell Volume  6
Issue  1 Pages  7-28
PubMed ID  14723844 Mgi Jnum  J:87967
Mgi Id  MGI:3028752 Doi  10.1016/s1534-5807(03)00399-x
Citation  Branda CS, et al. (2004) Talking about a revolution: The impact of site-specific recombinases on genetic analyses in mice. Dev Cell 6(1):7-28
abstractText  Site-specific recombinase systems (Cre-loxP, Flp-FRT, and phi C31-att) are transforming both forward and reverse genetics in mice. By enabling high-fidelity DNA modifications to be induced in vitro or in vivo, these systems have incited a wave of new biology, advancing our understanding of gene function, genetic relationships, development, and disease.
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