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Comment :

Type  MGI:General Description  at 3 months of age, mutant sciatic nerves show an increased number of small diameter axons relative to wild-type sciatic nerves in mutant sciatic nerves, a higher percentage of axons display a reduction in diameter (<1um) relative to wild-type sciatic nerves which display more axons with a diameter of >2um in addition, mutant sciatic nerves show a higher percentage of irregular fiber profiles relative to wild-type sciatic nerves (index of circularity, IC<0.75)