Type | MGI:General | Description | at 3 months of age, mutant sciatic nerves show an increased number of small diameter axons relative to wild-type sciatic nerves in mutant sciatic nerves, a higher percentage of axons display a reduction in diameter (<1um) relative to wild-type sciatic nerves which display more axons with a diameter of >2um in addition, mutant sciatic nerves show a higher percentage of irregular fiber profiles relative to wild-type sciatic nerves (index of circularity, IC<0.75) |