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Protein Coding Gene : Kpnb1 karyopherin subunit beta 1

Primary Identifier  MGI:107532 Organism  mouse, laboratory
Chromosome  11 NCBI Gene Number  16211
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.4.0)

Enables Hsp90 protein binding activity; importin-alpha family protein binding activity; and nuclear import signal receptor activity. Acts upstream of or within ribosomal protein import into nucleus. Located in cytoplasmic stress granule. Part of protein-containing complex. Is expressed in several structures, including gonad; metencephalon alar plate; neural retina; pancreas; and telencephalon. Orthologous to human KPNB1 (karyopherin subunit beta 1).
PHENOTYPE: Homozygous mutation of this gene results in lethality shortly after implantation. [provided by MGI curators]
  • synonyms:
  • Impnb,
  • Kpnb1,
  • AA409963,
  • expressed sequence AA409963,
  • MGI:2144006,
  • karyopherin subunit beta 1,
  • MGD-MRK-36102,
  • importin beta

Features --> Cross References

Genome

Sequence Feature Displayer

JG Browse Displayer

0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

1 Involved In Mutations

0 Strain

0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

25 Pathways

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

Other

0 Driver For