| First Author | Gallagher DS Jr | Year | 1992 |
| Journal | Genomics | Volume | 14 |
| Issue | 3 | Pages | 699-706 |
| PubMed ID | 1330890 | Mgi Jnum | J:3034 |
| Mgi Id | MGI:51549 | Doi | 10.1016/s0888-7543(05)80171-5 |
| Citation | Gallagher DS Jr, et al. (1992) Syntenic assignments of visual transduction genes in cattle. Genomics 14(3):699-706 |
| abstractText | To establish syntenic relationships of phototransduction genes, we have mapped the genes encoding the alpha-, beta-, and gamma-subunits of rod cGMP phosphodiesterase (PDE) (PDEA, PDEB, PDEG), the alpha'-subunit of cone PDE (PDEA2), and the rod cGMP-gated channel (CNCG) to bovine syntenic groups. The rod cGMP PDE alpha-, beta-, and gamma-subunit genes map to bovine syntenic groups U22, U15 (chromosome 6), and U21 (chromosome 19), respectively. The rod cGMP-gated channel gene also maps to syntenic group U15, and the bovine cone alpha'-subunit gene maps to U26 (chromosome 26). With the exception of the cone PDE alpha'-subunit gene, which has not been mapped in other mammals, all of these genes have been assigned to conserved chromosomal regions shared among bovine, human, and mouse. A compilation of currently known syntenic assignments and predictions regarding future assignments of phototransduction genes in human, mouse, and cattle is presented. |
