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Protein Coding Gene : Usp42 ubiquitin specific peptidase 42
Primary Identifier  MGI:1924050 Organism  mouse, laboratory
Chromosome  5 NCBI Gene Number  76800
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0)

Enables cysteine-type deubiquitinase activity. Predicted to be involved in regulation of apoptotic process. Predicted to act upstream of or within cell differentiation and proteolysis. Predicted to be active in cytosol and nucleus. Is expressed in several structures, including brain; eye; genitourinary system; gut; and hemolymphoid system gland. Orthologous to human USP42 (ubiquitin specific peptidase 42).
PHENOTYPE: Mice homozygous for a null allele exhibit fecundity and behavioral abnormalities, hyperactivity, increased T cell number, abnormal lens morphology, and cataracts. Males display oligozoospermia and testis degeneration. [provided by MGI curators]
  • synonyms:
  • 3110031A07Rik,
  • MGI:1261892,
  • A630018G05Rik,
  • D5Ertd591e,
  • RIKEN cDNA A630018G05 gene,
  • ubiquitin specific peptidase 42,
  • DNA segment, Chr 5, ERATO Doi 591, expressed,
  • MGI:2444457,
  • Usp42,
  • 2410140K03Rik,
  • RIKEN cDNA 3110031A07 gene,
  • MGI:1920429,
  • RIKEN cDNA 2410140K03 gene
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