| Primary Identifier | MGI:1913390 | Organism | mouse, laboratory |
| Chromosome | 11 | NCBI Gene Number | 66140 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0) Predicted to enable microtubule binding activity. Predicted to be involved in attachment of mitotic spindle microtubules to kinetochore; cell division; and regulation of microtubule polymerization or depolymerization. Predicted to be located in kinetochore. Predicted to be part of outer kinetochore. Predicted to be active in spindle microtubule. Is expressed in several structures, including alimentary system; brain; early conceptus; genitourinary system; and respiratory system. Orthologous to human SKA2 (spindle and kinetochore associated complex subunit 2). PHENOTYPE: Mice homozygous for a knock-out allele exhibit decreased embryo size, a rudimentary egg cylinder, failure of primitive streak formation, absent primitive node and head folds, failure to gastrulate, and complete lethality prior to organogenesis. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
