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Protein Coding Gene : Cenpo centromere protein O

Primary Identifier  MGI:1923800 Organism  mouse, laboratory
Chromosome  12 NCBI Gene Number  52504
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0)

Predicted to be involved in centromere complex assembly. Predicted to be located in nuclear body. Predicted to be part of Mis6-Sim4 complex. Is expressed in several structures, including central nervous system; genitourinary system; jaw; sensory organ; and thymus primordium. Orthologous to human CENPO (centromere protein O).
PHENOTYPE: Mice homozygous for a knock-out allele exhibit decreased embryo size, a rudimentary egg cylinder, failure of primitive streak formation, absent primitive node and head folds, failure to gastrulate, and complete lethality prior to organogenesis. [provided by MGI curators]
  • synonyms:
  • DNA segment, Chr 12, ERATO Doi 482, expressed,
  • Cenpo,
  • MGI:2144825,
  • 8430427C03Rik,
  • D12Ertd482e,
  • MGI:1918755,
  • RIKEN cDNA 8430427C03 gene,
  • MGI:1196418,
  • RIKEN cDNA 2810429O05 gene,
  • 2810429O05Rik,
  • centromere protein O

Features --> Cross References

Genome

Sequence Feature Displayer

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0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

0 Involved In Mutations

0 Strain

0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

21 Pathways

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

Other

0 Driver For