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Protein Coding Gene : Coro1c coronin, actin binding protein 1C

Primary Identifier  MGI:1345964 Organism  mouse, laboratory
Chromosome  5 NCBI Gene Number  23790
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.0.0)

Enables small GTPase binding activity. Involved in establishment of protein localization; regulation of fibroblast migration; and regulation of ruffle assembly. Acts upstream of or within corpus callosum development and ventricular system development. Located in cytoskeleton. Part of flotillin complex. Is expressed in several structures, including brain; dorsal root ganglion; genitourinary system; liver; and spleen. Orthologous to human CORO1C (coronin 1C).
PHENOTYPE: Mice exhibit reduced hearing sensitivity, reduced acoustic startle response, hypoactivity, and less frequent urination. [provided by MGI curators]
  • synonyms:
  • expressed sequence AW455561,
  • MGI:2141012,
  • MGI:2141223,
  • AW455561,
  • CRN2,
  • AW548837,
  • Coro1c,
  • expressed sequence AL022675,
  • AL022675,
  • expressed sequence AW548837,
  • coronin 3,
  • MGI:2141192,
  • coronin, actin binding protein 1C

Features --> Cross References

Genome

Sequence Feature Displayer

JG Browse Displayer

0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

2 Involved In Mutations

0 Strain

0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

0 Pathways

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

Other

0 Driver For