Primary Identifier | MGI:1914198 | Organism | mouse, laboratory |
Chromosome | 9 | NCBI Gene Number | 66948 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0) Predicted to enable 2-methylbutanoyl-CoA dehydrogenase activity; 2-methylpropanoyl-CoA dehydrogenase activity; and flavin adenine dinucleotide binding activity. Predicted to be involved in lipid metabolic process. Predicted to act upstream of or within branched-chain amino acid catabolic process. Located in mitochondrion. Is expressed in several structures, including alimentary system; genitourinary system; nervous system; respiratory system; and sensory organ. Orthologous to human ACAD8 (acyl-CoA dehydrogenase family member 8). PHENOTYPE: Mice homozygous for an ENU-induced allele exhibit cold intolerance at young age with a progressive hepatic steatosis and abnormal mitochondria. [provided by MGI curators] |