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Publication : Regional assignments of the zinc finger Y-linked gene (ZFY) and related sequences on human and mouse chromosomes.

First Author  Leung WY Year  1990
Journal  Cytogenet Cell Genet Volume  54
Issue  3-4 Pages  151-3
PubMed ID  2265557 Mgi Jnum  J:10907
Mgi Id  MGI:59351 Doi  10.1159/000132980
Citation  Leung WY, et al. (1990) Regional assignments of the zinc finger Y-linked gene (ZFY) and related sequences on human and mouse chromosomes. Cytogenet Cell Genet 54(3-4):151-3
abstractText  Recent chromosome walking experiments have identified a candidate gene (ZFY) for the testis-determining factor on the human Y chromosome (Page et al., 1987). We report here the regional assignments of the ZFY gene and related sequences in the human and the mouse. By in situ hybridization, we assigned ZFX and ZFY to human chromosome bands Xp21 and Yp11.3, respectively. Although the mouse harbors two Zfy genes, only one site at band A1 of its Y chromosome was significantly labeled. The mouse Zfx gene and the Zfa gene on chromosome 10 were assigned to bands XD and 10B5, respectively. These assignments of the ZFX gene in human and mouse add another marker to the conserved syntenic group for evaluating the evolutionary relationship of the human and mouse X chromosomes.
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