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Protein Coding Gene : Alppl2 alkaline phosphatase, placental-like 2
Primary Identifier  MGI:108009 Organism  mouse, laboratory
Chromosome  1 NCBI Gene Number  11650
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0)

Enables alkaline phosphatase activity. Located in myofibril. Is expressed in early conceptus; intestine; and testis. Human ortholog(s) of this gene implicated in inflammatory bowel disease. Orthologous to human ALPG (alkaline phosphatase, germ cell) and ALPI (alkaline phosphatase, intestinal).
PHENOTYPE: Mice homozygous for a knock-out allele exhibit strain background-dependent differences in the timing of preimplantation cleavage and development, embryo survival, gestational length and litter size. [provided by MGI curators]
  • synonyms:
  • Akp5,
  • Alppl2,
  • alkaline phosphatase, placental-like 2,
  • C77216,
  • D1Ertd816e,
  • MGI:2138659,
  • MGI:1289312,
  • alkaline phosphatase 5,
  • expressed sequence C77216,
  • MGD-MRK-37043,
  • DNA segment, Chr 1, ERATO Doi 816, expressed
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Features --> Cross References

Genome

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2 Involved In Mutations

Trail: ProteinCodingGene

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Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

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Function

Mouse features --> Functions (GO terms)

Homology

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Interactions

7 Pathways

Trail: ProteinCodingGene

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Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

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