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Protein Coding Gene : Neu2 neuraminidase 2

Primary Identifier  MGI:1344417 Organism  mouse, laboratory
Chromosome  1 NCBI Gene Number  23956
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.3.0)

Enables exo-alpha-(2->3)-sialidase activity and exo-alpha-(2->8)-sialidase activity. Involved in ganglioside catabolic process and oligosaccharide catabolic process. Predicted to be located in cytosol. Predicted to be part of catalytic complex. Predicted to be active in lysosome and membrane. Is expressed in brain. Orthologous to human NEU2 (neuraminidase 2).
PHENOTYPE: Homozygous null mice show increased triglyceride and free fatty acids with age, development of fatty liver, impaired muscle differentiation and altered muscle morphology, poor exercise performance and obesity with age. [provided by MGI curators]
  • synonyms:
  • cystolic sialidase,
  • MBS,
  • MTS,
  • brain sialidase,
  • Neu2,
  • MSS,
  • neuraminidase 2

Features --> Cross References

Genome

Sequence Feature Displayer

JG Browse Displayer

0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

2 Involved In Mutations

0 Strain

0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

11 Pathways

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

Other

0 Driver For