| Primary Identifier | MGI:1890645 | Organism | mouse, laboratory |
| Chromosome | 1 | NCBI Gene Number | 59125 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0) Enables molecular function activator activity. Involved in cellular response to potassium ion and positive regulation of NLRP3 inflammasome complex assembly. Located in cytoplasm and nucleus. Is expressed in several structures, including alimentary system; brain; genitourinary system; integumental system; and sensory organ. Orthologous to human NEK7 (NIMA related kinase 7). PHENOTYPE: Mice homozygous for an ENU-induced allele exhibit infertility, decreased susceptibility to EAE, decreased body weight, abnormal gait, slight parasis and abnormal immune system response. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
