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Protein Coding Gene : Ivns1abp influenza virus NS1A binding protein

Primary Identifier  MGI:2152389 Organism  Mus musculus
Chromosome  1 NCBI Gene Number  117198
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 3.2)

Involved in negative regulation of intrinsic apoptotic signaling pathway. Localizes to nucleus. Is expressed in several structures, including alimentary system; genitourinary system; musculoskeletal system; nervous system; and sensory organ. Human ortholog(s) of this gene implicated in immunodeficiency 70. Orthologous to human IVNS1ABP (influenza virus NS1A binding protein).
PHENOTYPE: Mice homozygous for a knock-out allele exhibit some early lethality, increased cellular sensitivity to cytochalasin and doxorubicin, and doxorubicin-induced cardiotoxicity. [provided by MGI curators]
  • synonyms:
  • NS-1,
  • AA960440,
  • Ivns1abp,
  • MGI:2138140,
  • 1190004M08Rik,
  • NS1-BP,
  • mKIAA0850,
  • 1700126I16Rik,
  • Nd1-L,
  • influenza virus NS1A binding protein,
  • expressed sequence AA960440,
  • MGI:1916149,
  • MGI:1920854,
  • RIKEN cDNA 1190004M08 gene,
  • RIKEN cDNA 1700126I16 gene,
  • ND1,
  • Nd1-S,
  • HSPC068

Features --> Cross References

Genome

Sequence Feature Displayer

JG Browse Displayer

0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

2 Involved In Mutations

0 Strain

0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

0 Pathways

508 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Mouse features --> Alleles

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications