Primary Identifier | MGI:1098272 | Organism | mouse, laboratory |
Chromosome | 1 | NCBI Gene Number | 24014 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0) Enables ribonucleoprotein complex binding activity. Acts upstream of or within fat cell differentiation; positive regulation of glucose import; and regulation of mRNA stability. Predicted to be located in nuclear matrix. Is expressed in cerebellum; embryo; hippocampus; retina inner nuclear layer; and retina outer nuclear layer. Human ortholog(s) of this gene implicated in Lynch syndrome and prostate cancer. Orthologous to human RNASEL (ribonuclease L). PHENOTYPE: Mice homozygous for disruptions in this gene have an enlarged spleen and increased succeptibility to viral infection. [provided by MGI curators] |