| Primary Identifier | MGI:1914200 | Organism | mouse, laboratory |
| Chromosome | 1 | NCBI Gene Number | 66950 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0) Enables pH-gated chloride channel activity. Involved in chloride transport. Acts upstream of or within chloride transmembrane transport. Predicted to be located in plasma membrane. Predicted to be part of chloride channel complex. Orthologous to human PACC1 (proton activated chloride channel 1). PHENOTYPE: Mice homozygous for a knock-out allele show absence of proton-activated Cl- (PAC) currents and decreased sensitivity to acid-induced cell death in primary cortical neurons, and decreased susceptibility to ischemic brain injury. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
