| Primary Identifier | MGI:107548 | Organism | mouse, laboratory |
| Chromosome | 1 | NCBI Gene Number | 22033 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.0.0) Predicted to enable enzyme binding activity; identical protein binding activity; and tumor necrosis factor receptor binding activity. Involved in interleukin-17-mediated signaling pathway; mRNA stabilization; and signal transduction involved in regulation of gene expression. Acts upstream of or within positive regulation of cell population proliferation and signal transduction. Located in cytoplasmic side of plasma membrane. Part of CD40 receptor complex. Is expressed in genitourinary system and tongue muscle. Orthologous to human TRAF5 (TNF receptor associated factor 5). PHENOTYPE: Homozygous null mice show defects in lymphocyte activation but are otherwise viable and develop normally. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
