|  Help  |  About  |  Contact Us

Protein Coding Gene : Vip vasoactive intestinal polypeptide

Primary Identifier  MGI:98933 Organism  mouse, laboratory
Chromosome  10 NCBI Gene Number  22353
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0)

Enables hormone activity. Involved in adenylate cyclase-activating G protein-coupled receptor signaling pathway; positive regulation of protein catabolic process; and regulation of protein localization. Acts upstream of or within regulation of signal transduction. Predicted to be located in neuronal cell body. Predicted to be active in neuron projection. Is expressed in several structures, including alimentary system; genitourinary system; hair root sheath; nervous system; and vomeronasal organ. Used to study primary pulmonary hypertension. Human ortholog(s) of this gene implicated in alcohol use disorder and pulmonary sarcoidosis. Orthologous to human VIP (vasoactive intestinal peptide).
PHENOTYPE: Homozygous null mutants display abnormal circadian rhythyms with a shorter period, abnormal phase, and in 1/4 arrhythmic circadian persistence. [provided by MGI curators]
  • synonyms:
  • vasoactive intestinal polypeptide,
  • MGD-MRK-15398,
  • Vip,
  • PHI, peptide histidine isoleucine

Features --> Cross References

Genome

Sequence Feature Displayer

JG Browse Displayer

0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

0 Involved In Mutations

0 Strain

0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

7 Pathways

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

Other

6 Driver For