| Primary Identifier | MGI:1328328 | Organism | mouse, laboratory |
| Chromosome | 10 | NCBI Gene Number | 17761 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.0.0) Enables signaling receptor binding activity. Involved in protein localization to plasma membrane and response to osmotic stress. Acts upstream of or within several processes, including glycosphingolipid metabolic process; male gonad development; and response to retinoic acid. Located in plasma membrane. Is expressed in several structures, including alimentary system; endocrine gland; genitourinary system; nervous system; and skin. Orthologous to human MAP7 (microtubule associated protein 7). PHENOTYPE: Males homozygous for mutations in this marker are sterile with small, disorganized testes, small epidiymis and seminiferous tubules. They have deformed spermatid nuclei and a block in spermatogenesis. Aberrant microtubules are seen in elongating spermatids and sertoli cells. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
