| Primary Identifier | MGI:96239 | Organism | mouse, laboratory |
| Chromosome | 10 | NCBI Gene Number | 15500 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.0.0) Enables RNA polymerase II cis-regulatory region sequence-specific DNA binding activity and identical protein binding activity. Acts upstream of or within spermatogenesis. Located in cytoplasm and nucleus. Is expressed in several structures, including central nervous system; future midbrain; genitourinary system; heart; and limb bud. Orthologous to human HSF2 (heat shock transcription factor 2). PHENOTYPE: Homozygotes for targeted null mutations exhibit increased late-gestational lethality associated with collapsed lateral ventricles and ventricular bleeding. Survivors may show ventricular dilation, sterility in females, and reduced sperm counts in males. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
