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Protein Coding Gene : Adamts14 ADAM metallopeptidase with thrombospondin type 1 motif 14

Primary Identifier  MGI:2179942 Organism  mouse, laboratory
Chromosome  10 NCBI Gene Number  237360
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.0.0)

Enables peptidase activity. Acts upstream of or within collagen fibril organization. Located in extracellular region. Is expressed in vertebral axis musculature. Human ortholog(s) of this gene implicated in osteoarthritis; primary progressive multiple sclerosis; and relapsing-remitting multiple sclerosis. Orthologous to human ADAMTS14 (ADAM metallopeptidase with thrombospondin type 1 motif 14).
PHENOTYPE: Mice homozygous for a knock-out allele are viable, healthy and fertile and exhibit normal aminoprocollagen processing. [provided by MGI curators]
  • synonyms:
  • Adamts-14,
  • TS14,
  • Adamts14,
  • ADAM metallopeptidase with thrombospondin type 1 motif 14

Features --> Cross References

Genome

Sequence Feature Displayer

JG Browse Displayer

0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

2 Involved In Mutations

0 Strain

0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

7 Pathways

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

Other

0 Driver For