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Protein Coding Gene : Arid5b AT-rich interaction domain 5B

Primary Identifier  MGI:2175912 Organism  mouse, laboratory
Chromosome  10 NCBI Gene Number  71371
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0)

Predicted to enable transcription cis-regulatory region binding activity and transcription coactivator activity. Involved in adipose tissue development. Acts upstream of or within several processes, including cellular response to leukemia inhibitory factor; face morphogenesis; and gonad development. Predicted to be active in nucleus. Is expressed in several structures, including alimentary system; embryo ectoderm; embryo mesenchyme; genitourinary system; and sensory organ. Orthologous to human ARID5B (AT-rich interaction domain 5B).
PHENOTYPE: Mice homozygous for disruptions in this gene experience a high level of mortality perinatally or earlier. Growth rates are low and mice remain small throughout live. There are abnormalities in various organ systems as well as the reproductive system. Fertility is reduced. [provided by MGI curators]
  • synonyms:
  • RIKEN cDNA 5430435G07 gene,
  • MGI:2143624,
  • AI467247,
  • Mrf2alpha,
  • expressed sequence AI467247,
  • Arid5b,
  • developmentally and sexually retarded with transient immune abnormalities,
  • MGI:1918621,
  • AT-rich interaction domain 5B,
  • Desrt,
  • Mrf2beta,
  • Mrf2,
  • 5430435G07Rik

Features --> Cross References

Genome

Sequence Feature Displayer

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0 Canonical

0 CDSs

0 Exons

0 Genomic Clusters

2 Involved In Mutations

0 Strain

0 Transcripts

0 Transgenic Expressors

0 UTRs

Canonical gene --> CDSs in specific strains.

Canonical gene --> Exons in specific strains

Canonical gene --> Strain-specific IDs, biotypes, and locations

Canonical gene --> Transcripts in specific strains.

Features --> Overlapping features

Proteins

Gene --> Proteins

Function

Mouse features --> Functions (GO terms)

Homology

Genes --> Homologs

Interactions

3 Pathways

0 Targeted By

Gene --> Protein-Protein Interactions

Expression

Gene --> Expression annotations

Phenotype

Genes/Features --> Phenotypes (MP terms)

Disease

Mouse features --> Human diseases

Literature

Mouse features --> Publications

 

Other

0 Driver For