| Primary Identifier | MGI:96897 | Organism | mouse, laboratory |
| Chromosome | 10 | NCBI Gene Number | 17105 |
| Mgi Type | protein coding gene |
| description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.3.0) Enables lysozyme activity. Involved in defense response to Gram-negative bacterium and defense response to Gram-positive bacterium. Predicted to be located in several cellular components, including Golgi cis cisterna; cytoplasmic vesicle; and rough endoplasmic reticulum lumen. Is expressed in several structures, including hematopoietic system; liver; mesothelium; small intestine; and yolk sac. Human ortholog(s) of this gene implicated in familial visceral amyloidosis. Orthologous to human LYZ (lysozyme). PHENOTYPE: Mice homozygous for a reporter allele exhibit increased inflammation in response to Micrococcus luteus and its peptidoglycan, despite partial compensatory expression of lysozyme P in macrophages. [provided by MGI curators] |
Features --> Cross References
Canonical gene --> CDSs in specific strains.
Canonical gene --> Exons in specific strains
Canonical gene --> Strain-specific IDs, biotypes, and locations
Canonical gene --> Transcripts in specific strains.
Features --> Overlapping features
