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Protein Coding Gene : Pan2 PAN2 poly(A) specific ribonuclease subunit
Primary Identifier  MGI:1918984 Organism  mouse, laboratory
Chromosome  10 NCBI Gene Number  103135
Mgi Type  protein coding gene
description  FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0)

Predicted to enable 3'-5'-RNA exonuclease activity. Predicted to contribute to poly(A)-specific ribonuclease activity. Predicted to be involved in nuclear-transcribed mRNA poly(A) tail shortening. Predicted to act upstream of or within nuclear-transcribed mRNA catabolic process. Located in P-body. Is expressed in 1-cell stage embryo; 2-cell stage embryo; 4-cell stage embryo; primary oocyte; and secondary oocyte. Orthologous to human PAN2 (poly(A) specific ribonuclease subunit PAN2).
PHENOTYPE: Mice homozygous for an ENU-induced allele exhibit embryonic lethality. [provided by MGI curators]
  • synonyms:
  • RIKEN cDNA 1200014O24 gene,
  • AW742773,
  • AI047843,
  • expressed sequence AW742773,
  • MGI:2143521,
  • MGI:2143882,
  • Pan2,
  • 1200014O24Rik,
  • PAN2 poly(A) specific ribonuclease subunit,
  • ubiquitin specific peptidase 52,
  • Usp52,
  • expressed sequence AI047843
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