Primary Identifier | MGI:1855701 | Organism | mouse, laboratory |
Chromosome | 11 | NCBI Gene Number | 53604 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0) Acts upstream of or within acrosome assembly and binding activity of sperm to zona pellucida. Located in acrosomal vesicle and cell body. Part of zona pellucida receptor complex. Human ortholog(s) of this gene implicated in spermatogenic failure. Orthologous to human ZPBP (zona pellucida binding protein). PHENOTYPE: Male mice homozygous for a null mutation display infertility and asthenoglobozoospermia. Heterozygous males display an increase in the percentage of abnormal sperm. [provided by MGI curators] |