Primary Identifier | MGI:96564 | Organism | mouse, laboratory |
Chromosome | 11 | NCBI Gene Number | 16199 |
Mgi Type | protein coding gene |
description | FUNCTION: Automated description from the Alliance of Genome Resources (Release 7.1.0) Enables interleukin-9 receptor activity. Acts upstream of or within several processes, including B cell activation; interleukin-9-mediated signaling pathway; and regulation of peptidyl-tyrosine phosphorylation. Located in cell surface and plasma membrane. Is expressed in bone marrow. Orthologous to human IL9R (interleukin 9 receptor). PHENOTYPE: Homozygous null mice are more susceptible to experimental autoimmune encephalomyelitis, a defect partially attributable to defective regulatory T cell function. [provided by MGI curators] |